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肌萎缩侧索硬化的动物模型

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摘要 肌萎缩侧索硬化的动物模型对研究该病的细胞与分子机制及评估治疗药物的有效性具关键作用。本文介绍5种自发性动物模型及3种实验诱发性模型,后者包括兴奋性氨基酸模型,自身免疫性模型及当今研究与使用较多的转基因模型。最后介绍38种用于实验模型的治疗药物。
作者 王文敏 王荪
出处 《国际神经病学神经外科学杂志》 2005年第4期341-344,共4页 Journal of International Neurology and Neurosurgery
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