放射诱导基因治疗肿瘤的研究进展

Advances of radiation-inducible gene therapy for tumor

近年来,放射诱导基因治疗已成为肿瘤治疗领域新的研究热点之一。该治疗策略一方面将放射治疗与基因治疗有机地结合,发挥协同治疗作用;另一方面由于放疗具有靶向性和可控性,实现了对杀伤基因表达的时空调控。相关的研究已经取得一定进展,作者简要概述目前的研究现状及该技术未来的应用前景。

Recently,radiation-inducible gene therapy is one of new researchs in tumor therapy. In one side, the method associate radiation therapy with gene therapy, acting as synergistic effect;another side, radiation is targeting and inducible,implementing spatial and temporal control of gene expression. Related researchs have gained advances. This paper concisely reviews the status quo and the prospective applications.