血脂异常的现代药物治疗

Modern pharmacotherapy of lipid abnormalities

血脂异常是引起动脉粥样硬化和冠心病最重要的危险因素。近年来其治疗药物发展迅速,新药不断应用于临床。作者分别就他汀类、贝特类等八类药物对血脂异常的调脂作用,尤其对新近研究开发的药物作一综述,并对这些药物的应用进行临床评价。

Lipid abnormality is a major risk factor of atherosclerosis and coronary heart disease. Pharmacological agents used to manage lipid abnormalities have been rapidly developed in recent years. Many new drugs have shown significant effects in the regulation of lipid abnormalities. Eight groups of drugs used to regulate lipid abnormalities were outlined in this paper, and the current recommendation for regulation of lipid abnormalities with some new drugs were discussed in details.