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Survivin、凋亡与泌尿系肿瘤 被引量:1

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摘要 细胞凋亡在维持机体自身稳定方面有重要作用,在肿瘤的发生发展中主要起负调控作用。肿瘤细胞的凋亡是当前研究的热点,而Survivin作为凋亡抑制蛋白家族(IAPs)的成员之一,其独特的分子结构及在肿瘤中特异性表达的特性,倍受关注。本文就其分子生物学特性与凋亡的关系及在泌尿系肿瘤的研究现状作一综述。
出处 《国外医学(泌尿系统分册)》 2005年第6期783-787,共5页 Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
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同被引文献4

  • 1宋涛,李鸣,石怀银,洪宝发,那彦群.凋亡抑制基因存活素在膀胱癌中的表达及意义[J].中华泌尿外科杂志,2004,25(12):848-850. 被引量:11
  • 2Ambrosini G, Adida C, Altieri DC. A novel anti-appoptosis gene, Survivin, expressed in cancer and lymphoma [J].Nat Med,1997,3 (8) :917.
  • 3Akhtar M, Gallagher L, Rohan S. Survivin: role in diagnosis, prognosis, and treatment of bladder cancer [J]. Adv Anat Pathol,2006,13 (3) : 122.
  • 4Swana HS, Grosman D, Anthony JN, et al. Tumor content of the anti-apoptosis molecule Survivinand recurrence of bladder cancer[ J]. N Eng J Med, 1999,341:452.

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