环氧化酶-2在膀胱移行细胞癌的临床研究进展
摘要
环氧化酶(COX)是前列腺素合成过程中的重要限速酶,目前至少已发现有两种同工酶:COX-1和COX-2。近年来的研究发现COX-2在多种癌症中高度表达,本文综述了COX-2在膀胱移行细胞癌的分级、分期、肿瘤预后以及其抑制剂应用前景等方面研究的最新进展。
出处
《国外医学(泌尿系统分册)》
2005年第6期789-792,共4页
Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
参考文献18
-
1Dannenberg A J, Altorki NK, Boyle JO, et al. C yclooxygenase-2: a pharmacological target fox the prevention of cancer. Lancet Oncol, 2001,2(9):544 - 551.
-
2Masfemer JL, Leahy KM, Koki AT, et al. Anti - angiogenin and anti-tumor activation of cyclooxygenase-2 inhibitors. Cancer Res,2000,60(5):1306.
-
3Gee JR, Montoya RG, Khaled HM, et al. Cytokeratin 20, AN43, PGDH and COX- 2 expression in transitional and squamous cell carcinoma of the bladder. Urol Oncol, 2003,21(4): 266 - 70.
-
4Mohammed SI, Knapp DW, Bost wick DG, et al. Expression of cyclooxygenase- 2(COX 2) in human invasive transitional cell carcinoma(TCC) of the urinary bladder. Cancer Res, 1999,59: 5647-5650.
-
5Dannenbexg AJ, Altorki NK, Boyle JO, et al. Cyclooxygenase-2: a pharmacological target fox the prevention of cancer. Lancet Onco1, 2001,2(9):544-551.
-
6Howe LR, Dannenberg At. A role for cyclooxygenase- 2 inhibitors in the prevention and treatment of cancer. Se min Oncol, 2002, 29(3 Suppl-11):111-119.
-
7Cao Y, Prescott SM. Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J Cell Physio1,2002,190(3):279-286.
-
8Shirahama T. Cyclooxygenase - 2 expression is up - regulated in transitional cell carcinomas and its preneoplastic lesions in human urinary bladder. Clin Cancer Res,2000,6:2424 - 2430.
-
9Kimhoff M, Guan Y, Shappell HW, et al. Enhanced expression of cyclooxygenase - 2 in high human transitional cell bladder carcinomas. Am J Pathol, 2000,157:29 - 35.
-
10Yoshimura R,Sano H, Mitsuhashi M,et al. Expression of cyclooxygenase-2 in patient with bladder cancer. J Lirol,2001,165,1468-1472.
-
1卓文利,靳风烁,李黔生,江军,张军卫,聂志林.膀胱移行细胞癌中COX-2的表达与其生物学行为的关系[J].医学临床研究,2004,21(7):744-747. 被引量:3
-
2花文玲,张鹏飞,徐惠贞.WWOX、P53在卵巢上皮性肿瘤中的表达及意义[J].中国误诊学杂志,2009,9(23):5548-5550.
-
3高青,刘兴,王丕龙.胃癌组织中环氧化酶-2的表达与微血管密度和VEGF的关系[J].肿瘤防治杂志,2004,11(1):65-68. 被引量:1
-
4徐学政,黄钢,刘剑帆,李林勍,罗毅.PTEN、COX-2及MMP-9在骨肉瘤中的表达及其意义[J].医学临床研究,2010,27(5):820-823.
-
5文芳,翁洁,胡建兵.COX-2、HER-2和VEGF在乳腺癌中的表达及其临床意义[J].医学临床研究,2010,27(7):1292-1294.
-
6王西京,代志军,赵世平,刘小旭,康华峰,薛锋杰.乳腺癌组织中环氧化酶-2的表达及其意义[J].肿瘤防治杂志,2004,11(12):1261-1263. 被引量:9
-
7豆道勤(综述),陈志坚(综述).食管鳞癌COX-2蛋白表达意义研究进展[J].国际肿瘤学杂志,2008,35(1):37-40.
-
8柳凤轩,于冬梅,金锡御,阎晓初,陈烯伟,刘平.30例膀胱移行细胞癌的超微结构观察[J].第三军医大学学报,1993,15(5):437-441. 被引量:1
-
9范玉玲,吕存义.原发肾盂移行上皮细胞癌52例报告[J].中华泌尿外科杂志,1992,13(2):89-91. 被引量:2
-
10俞俊杰,顾沈阳.血管内皮生长因子及其受体在膀胱移行细胞癌中的研究进展[J].国际泌尿系统杂志,2006,26(6):760-763. 被引量:1