湖北省2004年流感监测结果分析

Analysis of Influenza Epidemic in Hubei Province, 2004

目的掌握2004年湖北地区流感流行状况。方法收集及分析监测医院及暴发疫情资料,用鸡胚和细胞培养分离并鉴定流感病毒,用血球凝集抑制试验检测人群中抗流感病毒抗体水平。结果监测医院2004年流感样病例较往年增加,冬春和夏季可见2个波峰;各地报告发生疫情35起,15起疫情有56人经实验室检测确诊为流感病例,80%发生在中小学校;全年从936份标本中分离病毒123株,甲3型95株(占77.2%),乙型(yamagata株系)流感病毒28株(占22.8%);正常人群抗体水平测定以抗甲3抗体最高,抗甲1抗体最低。结论2004年湖北省流感活动较为活跃,流行毒株以甲3型病毒为主,并有向乙型转化的趋势。

Objective To understand and analyse the influenza epidemic in Hubei province in 2004. Methods To collect data and material from hospital and field survey. MDCK was used to isolate influenza virus from the samples and hemagglutination inhibition test was used to detect antibody level against influenza virus. Results The number of Influenza-Like Illness （ILI） was higher in 2004, there were two ILI peaks in 2004 （March and August）, 35 outbreaks of influenza were reported in 22 counties, 80% were in primary and middle schools, A3 was the main type. Conclusion Influenza was quite active in 2004 in Hubei; A3 type was the dominant strain. B type （Yamagata-like） was first isolated in March and was the dominant strain only after October.