四川省2001～2004年流感监测结果分析

Influenza Surveillance in Sichuan during 2001～2004

目的掌握流感在四川省的流行动态以及流行毒株变异情况,了解全省一般人群体内的流感抗体的消长情况,指导防治工作,达到预防控制流感。方法总结、分析流感流行病学监测、病原学监测和血清学监测资料。结果监测医院流感样病例ILI占门诊就诊总数的百分比,2001年高峰在冬季(51周)为41.67%,2002年在夏季(27周)高峰曾达到了52.53%。2003、2004年ILI百分比一直处于较低水平,而没有明显的季节性波动。甲1、甲3和乙型每年都有不同程度的流行,2001年乙型为优势毒株,2002年为甲1亚型,2003年又为乙型,2004年为甲3亚型。结论甲3亚型为优势毒株的年份流行强度较其它型别的强。高发季节以春季为主,冬季高峰近几年均不明显,易感人群为15岁以下儿童和婴幼儿,散发ILI和暴发ILI均以儿童和婴幼儿为主,中小学校是发生流感暴发疫情的高危场所。根据全省一般人群的流感抗体水平可以初步估计下一季节的流行趋势。

Objective To understand Influenza Epidemic,virus variance,and sero-epidemiology of people in different age groups,so as to prevent and control influenza in Sichuan. Methods By analyzing and evaluating the surveillance information during 2001 to 2004. Results The percentage of Influenza-Like Illness （ILI） in out-patient department was at the peak in winter （2001） and summer （2002）, the predominant influenza virus strain changed in every year, B for 2001 ,H1N1 for 2002,B for 2003 and H3N2 for 2004. Conclusion There were more influenza cases in every spring,H3N2 strain caused more cases than other strains. Most outbreaks happened in primary and middle schools, there fore, more attention should be paid to schools. The forecast of the epidemic strain for the coming year could be made through the sero-epidemiological analysis.