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测定Cyclophilin自身抗体的意义 被引量:8

Determination of anti-cyclophillin autoantibody and Its clinical significance
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摘要 自猪肾皮质提取Cyclophilin(CyP),建立了检测抗CyP的间接ELISA试验。SLE患者抗CyP阳性率为53.3%,显著高于类风湿性关节炎、桥本甲状腺炎与其他疾病患者。抗CyP与抗核抗体或抗钙调素抗体之间无相关关系(P>0.05)。 An indirect ELISA technique for detecting anti-cyclophilin (anti-CyP ) autoantibody was established by using the CyP isolated from porcine renal cortex. The positive rate of anti-CyP of the patients with systemic lupus erythematosus ( SLE ) was significantly higher then that of the patients with rheumatoid arthritis , Hashimoto' s thyroiditis and others. No significant correlation was found between anti CyP and anti-calmodulin or anti-nuclear antibody (P> 0. 05 ) .
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 1996年第1期63-65,共3页 Chinese Journal of Microbiology and Immunology
关键词 环孢素A 自身抗体 系统性红斑狼疮 红斑狼疮 Cyclosporin A Cyclophilin Autoantibody Systemic lupus erythematosus
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  • 1吴承军,中华医学检验杂志,1990年,13卷,94页
  • 2武建国,实用临床免疫学检验,1989年

共引文献3

同被引文献35

  • 1李晓军,武建国.抗钙调素自身抗体测定方法的建立及应用[J].中华医学检验杂志,1994,17(3):137-139. 被引量:4
  • 2刘铁榜,章华,臧德馨.精神分裂症感染及自身免疫因素研究进展(上)[J].临床精神医学杂志,1996,6(2):115-116. 被引量:7
  • 3刘铁榜,章华,臧德馨.精神分裂症感染及自身免疫因素研究进展(下)[J].临床精神医学杂志,1996,6(3):176-177. 被引量:3
  • 4叶任高,谢春.要重视对狼疮性肾炎的研究[J].中华内科杂志,1997,36(2):75-76. 被引量:44
  • 5许贤豪.神经免疫学[M].北京:北京医科大学中国协和医科大学联合出版社,1992.208.
  • 6叶丕妩 王毓三.全国临床检验操作规程[M].东南大学出版社,1997.388-395.
  • 7[1]Poser CM,Patty DW,Schreiber GL,et al.New diagnostic criteria for multiple sclerosis,guidelines for research protocols.Ann Neurol,1983,13(3):227-231.
  • 8[2]Harigai M,Hara M,Takahashi N,et al.Presence of autoantibodies to peptidyl-propyl cis-trans isomerase (cyclosporin A-binding protein) in system lupus erythematosus.Clin Immunol Immunopathol,1992,63(1):58-65.
  • 9[4]David W.Experimental allergie,encephalomyelitis in the Lewis rat:studies on the mechanism of recovery from disease and acquired resistance to reinduction.J Immunol,1979,123(3):1145-1150.
  • 10[5]Montague JW,Gaido ML,Frye C,et al.A calcium-dependent nuclease from apoptotic rat thymecytes is homologous with cyclophilin,recombinant cyclophilins A,band C have nuclease activity.J Biol Chem,1994,269(29):18799-18880.

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