摘要
为探讨神经植入术的机制,将2只恒河猴各手指先造成失神经支配,然后进行神经植入实验。结果:①神经纤维再生过程与以前兔的实验结果相似;②可再生触觉小体和上皮细胞轴突复合体两种感觉小体;③触觉小体再生率逐渐增加,形态结构也日趋成熟;④神经植入后6个月未见环层小体获得神经再支配;⑤移植的无毛皮肤亦可再生触觉小体。实验初次证明,灵长类动物失神经支配的无毛皮肤植入神经后,可以再生新的游离神经末梢以及触觉小体和上皮细胞-轴突复合体。
Two rhesus monkeys were used.Their fingers were denervated first and then the nerve was implanted into the denervated skin.The results showed that:(1)the process of regeneration of nerve fibers was similar to that of previous experiments in rabbits;(2)regeneration of nervous tissue included 2 kinds of sensory receptors with capsule-Meissner corpuscles and Merkel cell-dendrite complex;(3)the regenerative rate of Meissner corpuscles increased progressively and their morphology and structure be- came matured with elapse of time;(4)no regeneration of pacinian corpuscle was found in 6 months after nerve implantation;(5)Meissner corpuscles also regenerated in the transplanted glabrous skin.
关键词
感觉神经植入
神经再生
触觉小体
环层小体
Sensory nerve implantation
Nerve regeneration
Meissner corpuscle
Pacinian corpuscle
Merkel cell-dendrite complex
