交感性眼炎的荧光素眼底血管造影和吲哚菁绿血管造影观察

FFA and ICGA in sympathetic ophthalmia

目的 观察交感性眼炎的荧光素眼底血管造影(fundus fluorescein angiography, FFA)和吲哚菁绿血管造影(indocyanine green angiography, ICGA)特征。方法 选择交感性眼炎患者6例(6只眼)，进行FFA与ICGA的同步造影，并随访3月至2年。结果 初发病者FFA可出现视盘高荧光渗漏或荧光染色，黄斑暗区扩大，ICGA早期有脉络膜血管扩张，中后期有片状低荧光，或环以高荧光带。治疗后，FFA的渗漏灶可以很快消失，有透荧灶出现，ICGA则改变不明显，上述病灶仍存在，可出现多灶性的低荧光区，持续时间较长。结论 交感性眼炎主要表现为脉络膜炎。ICGA可更客观地反映交感性眼炎诊治情况。

Objective To investigate the characteristic of sympathetic ophthalmia by isochronous indocyanine green and fluorescein angiography （ICGA and FA）. Methods 6 sympathetic ophthalmia patients including 6 eyes were examined by Heidelberg retina angiography （ HRA ） and followed up from 3 to 24 months. Results 3 eyes of acute stage without any treatment may have no obvious changes in early phase in FFA. But they may present hyperfluorescence or mild fluorescence staining aroud the optic disc or uneven background in the mid and late phases. In ICGA, they present some hyperfluorescence area in the early phase and hypofluoreseence area around by hyperfluoreseence ring in the late phase. After treatment, there are no obvious changes but some transmitted fluorescence spots in FFA. However, those hypofluorescence area are still exist in ICGA. The hypofluorescence of ICGA is prominent and lasting in the follow - up period. Conclusion These characteristics of ICGA and FA suggest that sympathetic ophthalmia displays ehoroiditis mainly. ICGA can offer more objective evidence on diagnosis and therapy about this disease.