补阳还五汤对气虚血瘀型和非气虚血瘀型缺血性中风病人的疗效比较

Comparison of the Effects of Buyanghuanwu Decoction on Ischemic Apoplexy with Different Patterns

目的研究补阳还五汤对气虚血瘀型和非气虚血瘀型缺血性中风病人血清超氧化物歧化酶(SOD)和丙二醛(MDA)的影响。方法检测经补阳还五汤治疗后气虚血瘀型和非气虚血瘀型缺血性中风病人(各130例)血清SOD、MDA含量,比较补阳还五汤对两型病人血清SOD、MDA的影响。结果气虚血瘀组经补阳还五汤治疗后SOD由(51.23±9.96)nU/mL升至(96.84±10.86)nU/mL,MDA由(8.71±2.28)nM/mL降至(4.16±1.8)nM/mL(P<0.01);非气虚血瘀组经补阳还五汤治疗后SOD由(50.97±9.69)nU/mL升至(92.14±10.15)nU/mL,MDA由(8.65±2.40)nM/mL降至(4.01±1.2)nM/mL(P<0.01)。治疗后气虚血瘀组总有效率为86.2%,非气虚血瘀组为84.6%,两组比较无统计学意义。结论补阳还五汤对两型缺血性中风人均有治疗作用。

Objective To study the influence of Buyanghuanwu Decoction on Content of serum SOD and MDA in patients （pts） with ischemic apoplexy with （groupl） and without （group2） Qi- Deficiency Causes Blood Stasis. Method SOD and MDA in serum were determined in 130 pts with ischemic apoplexy with Qi - Deficiency Causes Blood Stasis pre - and post - therapy of Buyanghuanwu Decoction, and compared with that in 130 pts without Qi- Deficiency Causes Blood Stasis. Results Following the therapy SOD was decreased （from 51.23 ± 9.96 nU/mL to 96.84 ± 10.86 nU/mL） in group 1 and （from 50.97 ± 9.69 nU/mL to 92.14 ± 10.15 nU/mL） in group 2. The MDA was lowered（from 8.71 ± 2.28 nM/mL to 4.16 ± 1.87 nM/mL） in group 1 and （from 8.65 ± 2.40 nM/mL to 4.01 ± 1.27nM/mL） in group 2. There was no difference （P 〉 0. 05 ）. Conclusion The effect of Buyanghuanwu Decoction for pts with Ischemic Apoplexy with Qi- Deficiency Causes Blood Stasis is not better than that for the pts without Qi - Deficiency Causes Blood Stasis.