1Cutolo M, Sulli A, Seriolo B, et al. Sex hormones, proto-oncogene expression and apoptosis: their effects on rheumatoid synovial tissue. Clin Exp Rheumatol , 1996,14:87
2Kanda N,Tamaki K. Estrogen enhances immunoglobulin production by human PBMCS. J Allergy Clin Immunol, 1999,103: 282
3Jansson L, Holmdahl R. Estrogen-mediated immunosuppression in auto-immune diseases. Inflamm Res, 1998,47:290
4Iller RA: Immune system;in Masoro E(ed) :Handbook of Physiology Aging. New York:Oxford University Press, 1995,555
5Kamada M, Irahara M,Maegawa M, et al. Effect of hormone replacement therapy on postmenopausal changes of lymphocytes and T-cell subsets. J Endocrinol Invest,2000,23: 376
6Kamada M, Irahara M,Maegawa M, et al. Transient increase in the levels of T-helper 1 cytokines in postmenopausal women and the effects of hormone replacement. Therapy Gynecol and Obstet Invest ,2001,52:82
7Mosman TR, Coffman RL. TH1 and TH2 cells: Different pattans of lymphokine secretion lead to different functional properties. Annu Rev Immunal , 1989,7:145
8Abbas AK, Kenneth M, Sher M, et al. Functional diversity of helper T lymphocytes. Nature, 1996,383: 787
9Liu TF,Jones BM,Wong RW, et al. Impaired production of IL-12in systemic lupus erythematosus. Ⅲ. Deficient IL-12 p40 gene expression and cross-regulation of IL-12, IL-10 and IFN-gamma gene expression. Cytokine, 1999,11: 805
10De Groote D, Zangerle PF, Gevaert Y, et al. Direct stimulation of cytokins(IL-1bata and TNF-alfa, IL-6, IL-2, IFN-Gamma and GMCSF)in whole blood. Comparisons with isolated PBMC stimulation.Cytokine, 1992,4: 239
二级参考文献20
1金冬燕 黎孟枫译.分子克隆实验指南(第二版)[M].北京：科学出版社,1996.888.
2许溟宇，中华结核和呼吸杂志，1993年，16卷，284页
3Offner H, Adland K, Zamora A, et al. Estrogen potentiates treatmentwith T-cell receptnr protein of female mice with experimental encephalomyelitis [J]. J Clin Invest, 2000, 105(10): 1465 - 1472.
4Confavreux C, Hutchinson M, Hours MM, et al. Relapses and progression of disability in multiple sclerosis [ J ]. N Engl J Med, 2000,343 (20): 1430 - 1438.
6Piccinni MP, Scaletti C, Maggi E, et al. Role of hormone-controlledTh1- and Th2-type cytokines in successful pregnancy[ J ]. J Neuroimmunol, 2000, 109( 1 ): 30 -33.
7McBride JM, Jung T, de Vries JE, et al. IL-10 alters DC function viamodulation of cell surface molecules resulting in impaired T-cell responses [J]. Cell Immunol, 2002, 215(2): 162 - 172.
8Piemonti L, Monti P, Sironi M, et al. Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendriticcells [J]. J Immunol, 2000, 164(9): 4443 -4451.
9Gilmore W, Weiner LP, Correale J. Effect of estradiol on cytokine secretion by proteolipid protein-specific T cell clones isolated from multiple sclerosis patients and normal control subjects [ J ]. J Immunol,1997, 158(1): 446 -451.
10Baeuerle PA, Henkel T. Function and activation of NF- kappa B inthe immune system [J]. Annu Rev Immunol, 1994, 12:141 -179.
8Cuesta A,Vargas-Chacoff L,Arjona FJ,et al.Effect of sex-steroid hormones,testosterone and estradiol,on humoral immune parameters of gilthead seabream[J].Fish & Shellfish Immunology,2007,23(3):693.
9Minna S,John A.C,Kari KL,et al.Disruption of sexual selection in sand gobies (Pomatoschistus minutus) by 17α-ethinyl estradiol,an endocrine disruptor[J].Hormones and Behavior,2009,55(4):530.
10Freudenberger T, Deenen R, Kretschmer I, et al. Syn-thetic gestagens exert differential effects on arterial thrombosis and aortic gene expression in ovariectomized apolipoprotein E-deficient mice[J]. Br J Pharmacol,2014, 171 (22): 5032-5048.
