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GH/IGF-1治疗心力衰竭作用机制的研究进展 被引量：3

Mechanism of Growth Hormone and Insulin-like Growth Factors-1 in Treatment of Heart Failure
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摘要 生长激素(growth hormone,GH)是腺垂体合成和分泌的重要激素之一,大部分通过其介质胰岛素样生长因子-1(insu lin-like growth factors-1,IGF-1)发挥作用。GH/IGF-1对心血管系统具有促进心肌生长,增强心肌收缩力等特殊效应。因而在心力衰竭的治疗中有着重要的价值,现对GH/IGF-1治疗心力衰竭的可能机制作一综述。 Growth hormone（GH） ,a kind of important hormone,is synthesized and excreted by gland hypophysis. Most of it works by its medium insulin-like growth factors-1 （ IGF-1） to achieve its aim. GH and IGF-1 can increase left-ventricular wall thickness and improve cardiac function and exercise capacity. So GH and IGF-1 play important roles in the treatment of heart failure. This review describes the mechanism of GH and IGF-1 in treatment of heart failure.
作者 秦薇 蔡久英
机构地区 锦州医学院附属第一医院心脏病诊治中心
出处 《心血管病学进展》 CAS 2005年第6期578-581,共4页 Advances in Cardiovascular Diseases
关键词 生长激素 胰岛素样生长因子-1 心力衰竭 Growth hormone Insulin-like growth factor-1 Heart failure
分类号 R541.6 [医药卫生—心血管疾病]
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共引文献23

同被引文献41

  • 1王建安,谢小洁,何红,孙勇,蒋峻,骆荣华,樊友启,董樑.骨髓间质干细胞移植治疗原发性扩张型心肌病的疗效与安全性[J].中华心血管病杂志,2006,34(2):107-110. 被引量：44
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心血管病学进展
2005年 第6期

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