阿司匹林抵抗——治疗心血管疾病中不容忽视的因素

Aspirin Resistance——A Very Important Factor That Can′t be Ignored in Treatment of Cardiovascular Disease

阿司匹林在心血管疾病的预防和治疗中起着非常重要的作用,但阿司匹林抵抗的出现限制了其临床疗效,这一现象已越来越受到中外医学界的重视,现就阿司匹林抵抗的定义与分类、检测方法、发生机制、临床意义及未来展望作了比较详细的综述,对治疗心血管疾病的临床医生有一定的参考价值。

Although aspirin plays a very important role in prevention and treatment of cardiovascular disease,aspirin resistance limits its clinical benefits. This phenomenon draws increasing attention of the medical community in China and the world. This article particularly explains the aspirin resistance on its definition, class, detecting method, possible mechanisms, clinical significance, and future expectation, which is useful for reference to clinical practitioners of cardiovascular disease.