胆红素与冠心病相关性的研究进展

Advances of Relationship Between Bilirubin and Coronary Heart Disease

胆红素作为有效的脂溶性抗氧化剂,具有抑制低密度脂蛋白氧化和动脉粥样硬化的作用。现就血浆胆红素水平与冠心病及其并发症的相关性,胆红素与血脂、炎症和吸烟等冠心病危险因素的关系以及相关的分子生物研究进展进行综述。

As an effective lipid-soluble antioxidant,bilirubin can inhibit the oxidation of lower density lipoprotein and atherosclerosis. The correlation between plasma bilirubin level and coronary heart disease and its complications,and the relations between bilirubin and plasma lipids,inflammation, smoking and some other dangerous factors of coronary artery disease were reviewed in this paper. In addition, some related advances of molecular biology on the relations between bilirubin and coronary heart disease was also briefly introduced.