摘要
Duox2蛋白是在甲状腺滤泡细胞质膜顶部表达的一类膜蛋白,是钙依赖性辅酶Ⅱ(Ca2+/NADPH)氧化酶的催化活性部分,催化合成H2O2,为碘有机化过程提供电子受体。Duox2蛋白受碘、促甲状腺激素、钙离子等因素的调节。DUOX2基因突变是先天性甲状腺功能减退的发病机制之一。
出处
《国外医学（内分泌学分册）》
2005年第6期365-367,共3页
Foreign Medical Sciences(Section of Endocrinology)
参考文献17
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同被引文献3
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