少见类型乳腺癌病理组织学分析

A report of breast carcinoma with rare pathologic diagnosis

目的:探讨少见类型乳腺癌临床病理特点及鉴别诊断要点。方法:参照WHO肿瘤新分类标准,将42例少见类型的乳腺癌进行临床资料整理和病理学相关检查。结果:回顾42例乳腺癌病理切片,发现富含糖原的透明细胞癌9例,黏液癌4例,小管癌2例,化生性癌18例,大汗腺样癌6例,分泌型癌1例,富脂质癌2例;不同组织类型的乳腺癌具有不同的光镜、特殊染色及电镜表现。结论:明确少见不同组织类型乳腺癌有助于指导临床治疗及估计预后。

Objective：To study the ,clinical pathologic characteristics and differential diagnosis of rare type carcinoma of the breast. Methods：According to the new World Health Organization Classification of Tumors（ 2003 ） , 42 cases of rare type carcinoma of the breast were studied by clinical data and correlated investigation of pathology. Results： All the slides of the breast carcinoma in our department were reviewed, 9 cases of glycogenich, clear cell carcinoma, 4 cases of mucinous carcinoma, 2 cases of tubular carcinoma, 18 cases of metaplastic carcinoma, 6 cases of apocrine carcinoma, 1 case of secretary carcinoma, and 2cases of lipid-rich carcinoma were found. Different histologic type has different appearance in the light microscopy, special staining and electromicroscopy. Conclusion：Definite histological classification of breast carcinoma will be helpful in guiding the clinical treatment and estimating patients＂ prognosis.