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生物制剂治疗系统性红斑狼疮的研究进展 被引量：3

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摘要 近年来生物靶向疗法已用于治疗自身免疫性疾病,但该类药物成功治疗SLE的道路还很漫长,原因是SLE发病机制尚未完全阐明。生物靶向疗法是针对自身免疫性疾病免疫反应的不同环节:如针对清除B细胞,阻断T-B细胞之间相互作用,阻断细胞因子,改变独特型抗体,诱导对DNA、Ig-肽和肽类的耐受性。生物制剂治疗自身免疫性疾病尚处在初级阶段,本文对部分生物制剂治疗SLE最新进展作了综述。
作者 吴梅 赵传靖 赵天恩
机构地区 山东省皮肤病性病防治研究所 山东省济南市平阴县皮肤病防治站
出处 《中国麻风皮肤病杂志》 2005年第10期799-802,共4页 China Journal of Leprosy and Skin Diseases
关键词 抗-Blys抗体 抗-CD154抗体 抗IL-10抗体 生物制剂IVIG LJP 394 SLE抗-CD20抗体 生物制剂 系统性红斑狼疮 治疗
分类号 R593.241 [医药卫生—内科学]
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参考文献23

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同被引文献25

  • 1穆荣,戴振鹏,栗占国,高晓明.T细胞疫苗治疗系统性红斑狼疮的初步临床研究[J].中华内科杂志,2004,43(8):568-571. 被引量：7
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中国麻风皮肤病杂志
2005年 第10期

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