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克雷伯氏菌暴发感染和实验研究

CLINICAL AND LABORATORY STUDIES OF THE OUTBREAK OF KLEBSIELLA PNEUMONIAE INFECTION
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摘要 对某产婴室暴发医源性肺炎克雷伯氏菌感染作一调查,发现新生儿感染率达21.67%;以脐炎,结膜炎为主,2例死于败血症。收集自产婴室和其他病室的56株菌的耐药谱分7型,5种噬菌体将56株菌分成12型,流行株和散发株间型别有显著性差异。质粒分型在36种以上;流行株含2种质粒,酶切图谱近似,系同源株。 rom September to October in l990,an outbreak of Klebsiella pneumoniae infection occurredin the Neonatal Unit of Obstetrical Department in our hospital.The morbidity rate was 2l.67%. Omphalitis and conjunctivitis were the main clinical manifestations. Two neonates died of sep-ticemia. The 56 strains which resisted to l6 antibiotics were classified into 7 types;these strainswere again divided into l2 types by 5 phages of KP. There was significant difference in types be-tween epidemic and sporadic strains,The isolation rate of plasmid was 85.7l%and more than 36types were discovered.Epidemic strains containing 2 plasmids with similar enzymatic-cleavagefingerprintings were considered as hOmologous strains.
出处 《湖南医科大学学报》 CSCD 1996年第1期17-20,共4页 Bulletin of Hunan Medical University
关键词 克雷伯氏菌 肺炎杆菌 新生儿 流行病学 分型 Klebsiella pneumoniae nurseries,hospital epidemiology bacterial typing techniques drug resistance,microbial bacteriophage plasmids
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参考文献1

  • 1潘若男,中华微生物学和免疫学杂志,1988年,8卷,5期,232页

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