摘要
根据颞下颌关节紊乱综合征(temporomandibularjointdisturbancesyndrome,TMJDS)患者的关节液内存在免疫和炎症物质等研究成果,改进传统的关节封闭术,用关节腔冲洗-封闭疗法治疗43例TMJDS,取得了良好的治疗效果,并以传统的封闭法和单纯关节腔冲洗法作配对比较,证明其差异有显著性(P值分别小于0.01和0.05)。为探讨治疗机理,还对8例患者作了治疗前后关节液肿瘤坏死因子(TNF)测定,其差异有高度显著性(P<0.005)。认为关节腔冲洗和糖皮质激素封闭有协同或累加作用。关节腔冲洗-封闭疗法操作方便,疗效好。
Accordingtotheresearchthatthereweresomeimmuneandinflammatorysubstancesinthesynovialfluidoftemporomandibularjointdisturbancesyndrome(TMJDS),weimprovedthetraditionalintraarticularinjectionanddevelopedanintraarticularirrigation-injectiontherapytotreat43casesofTMJDSandgotagoodresult.Thecontrolsincludetwogroups,thesimplerinsingandthetraditionalinjection.Statisticalanalysisshowedahighlysignificantdiferenceintheefectsbe-tweentestandcontrolgroups.Inordertostudythemechanismofthetherapy,thetumornecrosisfactor(TNF)insynovialfluidof8caseswereassessed.ItwasfoundthattheconcentrationofTNFwasreducedmarkedlyaftertreatment.WethinkthatthenewtherapyisefectableforTMJDSandcouldbeusedwidely.
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
1996年第2期78-80,共3页
Chinese Journal of Stomatology
关键词
颞颌关节紊乱
关节腔冲洗
封闭疗法
TemporomandibularjointdisturbancesyndromeIntraaticularirrigationIn-traarticularinjectionTumornecrosisfactor