舍格伦综合征患者腮腺造影追踪观察

Sialographicfolow┐upstudyofpatientswithSjogren'ssyndrome

作者报告３６例舍格伦综合征Ｘ线追踪观察结果。追踪时间５～７２个月，平均２５个月。参考国际分类标准将患者分为三组：继发组１４例（眼干或（和）口干及结缔组织病）；原发组１４例（口干和眼干）；可能组８例（仅口干或眼干）。追踪结果各组Ｘ线表现：①形态无改变，功能更加迟缓，最早可发生在５个月后；②末梢导管点状扩张（点扩）增多；③点状扩张减少，末梢导管球状扩张（球扩）增多；④点、球、腔扩及阴性涎石；⑤向心性萎缩。本组资料显示：①眼干及结缔组织病继发组、仅眼干的可能组内，对腮腺影响不大，造影改变不明显，无点状扩张，而呈阴性涎石伴管炎改变，要结合临床才能与慢性阻塞性腮腺炎鉴别；②总唾液流率与腮腺造影改变呈负相关关系，总唾液流率低者腮腺造影点扩多，反之亦然。

Sialographicfolow-upstudiesof36casesofSjogren'ssyndrome(SS)wereperformedwiththedurationof5～72months(mean25months).Threegroupsweredividedaccordingtotheintenationalcriteria:secondarygroup,14cases(xerophthalmia,or/andxerostomia,andconnectivetissuediseases),primarygroup,14cases(xerostomiaandxerophthalmia),andpossiblegroup,8cases(xerophthalmiaorxerostomiaonly).Sialographicfindingsatfolow-upexaminationincluded(1)delayedevacuation,whichmayoccurasearlyas5monthslater;(2)increasedpunctatesialecta-sis;(3)decreasedpunctatesialectasiswithglobularincrease;(4)Punctate,globular,andcavitysialectasiswithradiolucentsialolith;and(5)centripetalatrophy.Thecaseswithsecondaryandpos-sibleSSwithoutxerostomiademonstratedlitleinvolvementoftheparotidgland,withoutsialectasis.Butsialodochitiswasshownwhenradiolucentsialolithformed.Thestimulatedwholesalivaryflowrate(SWSFR)wascloselyrelatedtosialographicappearance,i.e.,thecaseswithlowervalueofSWSFRshowedmoresialectasissialographicaly,butwithhigherSWSFRvalue,andlesssialectasis.