呼吸体操改善呼吸肌功能的量化研究

AQUANTITATIVESTUDYONTHEEFFECTOFBREATHINGEXERCISESINEMPROVINGRESPI┐RATORYMUSCLECONTRATION

为改善慢性阻塞性肺疾病（ＣＯＰＤ）缓解期患者呼吸肌肌力，兹选取３２４例ＣＯＰＤ患者进行呼吸体操锻炼。将ＣＯＰＤ患者随机分为呼吸体操组（１６５例）及安慰剂组（１５９例）。呼吸体操组患者经过１～２０个月的锻炼后，进行呼吸压及跨膈压的对比。结果发现最大吸气口腔压（ＭＩＰ）提高３０．４２％，最大呼气口腔压（ＭＥＰ）提高３２．１０％，跨膈压（Ｐｄｉ）提高３０．９４％，最大跨膈压（Ｐｄｉｍａｘ）次提高６５．５９％，与治疗前比较，差异有非常显著性（Ｐ＜０．００１）；对照组患者的ＭＩＰ、ＭＥＰ、Ｐｄｉ和Ｐｄｉｍａｘ提高６．９５％、２．９２％、１４．６３％及９．０５％，与治疗前比较，差异无显著性（Ｐ＞０．０５）。经量化标定后阐明呼吸体操可以作为ＣＯＰＤ缓解期患者防止复发和治疗方法之一，似为国内外首创。

Tostudyquantitativelytheefectofbreathingexercisesonthepreventionofprogresioninchronicobstructivepulmonarydisease(COPD).324patientswithstableCOPDwererandomlyassignedtoeitherbreathingexercises(BE)orplacebomedicineascontrol.Themaximumrespiratorypresure(320cas-es)andtransdiaphragmaticpressure(129cases)weremonitoredwithRMS-1andType-2gastroin-testinalpressuremeasuringinstrument.BEweretaughtandcheckedbyexperiencedspecialistsperiodi-caly.Pa-tientsinBEgroupwerecomparedwiththoseinthecontrolgroupbymeasuringMIP,MEP,Pdi,andPdimaxafteroneto20months.InBEgroupMIPincreasedby30.42%,MEP32.10%,Pdi30.94%,andPdimax65.59%(P<0.001).Nosignificantchangewasobservedinthecontrolgroup.MIP,MEP,Pdi,andPdimaxincreasedby6.95%,2.92%,14.63%and9.05%respectively(P<0.05)inthecontrolgroup.ItisshownpreliminarilythatBEhadpotentandlastingefectonrespiratorymusclecontractionafterstudyinglargenumberofcases.Themethodsmentionedabovecanbeusedasquantitativeindicesforthecontractileprop-ertiesofrespiratorymuscle.