1Siddiqui AQ,Ballatore C,McGuigan C,et al. The presence of substituent on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-Hiv efficacy in cell culture:A structure-activity relationship [J]. J . Med. Chem. 1999,42:393.
3Siddiqui A, McGuigan C, BallatoreC, et al. Enhancing the Aqueous Solubility of d4T-dased Phosphoramidate Prodrug[J] . Bio. Med. Chem. Lett, 2000, 10 : 381.
9Yoshiaki T, Yoshinari T. Synthesis of (3' R)- 3'-deoxy-3'-C-nitromethylthymidine[J]. Carbohydrate Research, 1995,270:77.
10Van Aerschot A, Herdewijn P, Pauwels R, et al. 3'-Fluoro-2', 3'-Dideoxy - 5-chlorouridine: Most Selective Anti-HIV-1Agent among a Series of New 2·, 3·-Dideoxynucleoside Analogues [J] . J. Med. Chem, 1989,32:1743.
二级参考文献29
1Graeme M. The emerging roles of non-nucleoside reverse transcriptase inhibitors in antiretroviral therapy[J]. Drugs, 2001,61(1):19-26.
2De Clercq E. Antiviral drugs: current state of the art [J].J Clin Virol ,2001,22(1) :73-89.
3Karen M, Caroline MP. Oseltamivir: a review of its use in influenza[J].Drugs ,2001,61(2) :263-283.
4Mckimm-Breschkin JL. Neuraminidase inhibitors for the treatment and prevention of influenza[J]. Expert Opin Pharmacother ,2002,3(2):103-112.
5Martin K, René T. New, azide-free transformation of epoxides into 1,2-diamino compounds: synthesis of the anti-influenza neuraminidase inhibitor oseltamivir phosphate(Tamiflu)[J].J Org Chem,2001,66:2044-2051.
6Choi WS, Im GJ, Kim TK, et al. Pharmacokinetic studies of 2-amino-9-(3-acetoxymethyl-4-isopropoxycarbonyb oxybut-1-yl)purine,an oral prodrug for the antiviral agent penciclovir[J].Drug Metab Dispos, 2001,29(7):945-949.
7Tak RV, Pal D, Gao HE, et al. Transport of acylclovir ester prodrugs through rabbit cornea and SIRC-rabbit corneal epithelial cell line[J].J Pharm Sci ,2001,90(10): 1505-1515.
8Curran M, Noble S. Valganciclovir[J].Drugs, 2001,61(8):1145-1150.
9Fiume L, Di Stefano G, Busi C, et al. Liver targeting of antiviral nucleoside analogues through the asialogly coprotein recepter[J].J Viral Hepat ,1997,4(6):363-370.
10Bijsterbosch MK, van de Bilt H, van Berkel TJ, et al. Specific targeting of a lipophilic prodrug of iododeoxyuridine to parenchymal liver cells using lactosylated reconstituted high density lipoprotein particles[J ].Biochem Pharmacol, 1996,52 (1):113-121.