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卵巢癌和小细胞肺癌治疗药belotecan 被引量:1

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摘要 1开发与上市厂商 本品由韩国钟根堂制药公司研制,于2004年10月在韩国首次上市.
作者 赖树清 须媚
出处 《世界临床药物》 CAS 2005年第11期699-699,共1页 World Clinical Drug
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  • 1冯乙巳,徐超,储玲玲,马志龙,杨庆华.喜树碱衍生物的研究进展[J].合肥工业大学学报(自然科学版),2007,30(5):579-582. 被引量:6
  • 2黄敏,丁健.拓扑异构酶Ⅰ抑制剂研究进展[J].中国新药杂志,2007,16(13):990-1000. 被引量:4
  • 3姜琦,王海翔.喜树碱类药物的现代研究进展[J].药学进展,2007,31(9):408-412. 被引量:6
  • 4Sang-sup Jew, Hee-Jin Kim, Myoung Goo Kim, et al. Synthesis and antitumor activity of 7-substituted 20(RS)-camptothecin analogues[J]. Bioorganic and Medicinal Chemistry Letters, 1996, 6(7): 845-848.
  • 5Sang-sup Jew, Kwang-dae Ok, Hee-jin Kim, et al. Enantioselective synthesis of 20(S)-camptothecin using sharpless catalytic asymmetric dihydroxylation[J]. Tetrahedron: Asymmetry, 1995, 6(6): 1245-1248.
  • 6Soon Kil Ahn, Nam Song Choi, Byeong Seon Jeong, et al. Practical synthesis of (S)-7-(2-isopropylamino)ethyl camptothecin hydrochloride, potent topoisomerase I inhibitor[J]. J Heterocyclic Chem, 2000, 37: 1141-1144.
  • 7Seigo SAWADA, Ken-ichiro NOKATA, Tomio FURUTA, et al. Chemical modification of an Antitumor alkaloid camptothecin: synthesis and antitumor activity of 7-C-substituted camptothecins[J]. Chem Pharm Bull, 1991, 39(10): 2574-2580.
  • 8Hee-Jung Ban, ln-Jae Oh, Kyu-Sik Kim, et al. Clinical efficacy of Belotecan(CKD-602), newly developed camptothecin analog, in the 2nd line treatment of relapsed small cell lung cancer[J]. Tuberculosis and Respiratory Diseases, 2009, 66(2): 93-97.
  • 9J C Kim, D H Shin, S H Kim, et al. Subacute toxicity evaluation of a new camptothecin anticancer agent CKD-602 administered by intravenous injection to rats[J]. Regulatory Toxicology and Pharmacology, 2004, 40: 356-369.
  • 10Moon-Koo Chung, Jong-Choon Kim, Sang-Seop Han. Embryotoxic effects ofCKD-602, a new camptothecin anticancer agent, in rats[J]. Reproductive Toxicology, 2005, 20: 165-173.

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