2-芳胺基-5-(3′-对甲氧基苯基-5′-甲基-异口恶唑-4′-基)-6H-1,3,4-噻二嗪的合成

Synthesis of Some 2-Arylamino-5-(3′-p-methoxyphenyl-5′-methyl Isoxazole-4′-yl)-6H-1,3,4-thiadiazines

以1-(3-对甲氧基苯基-5-甲基-异口恶唑-4-基)-乙酮(4)为原料与N4-芳基氨基硫脲缩合,生成一系列缩氨基硫脲化合物,与B r2/CHC l3环合,得到了一系列2-芳胺基-5-(3′-对甲氧基苯基-5′-甲基-异口恶唑-4′-基)-6H-1,3,4-噻二嗪的化合物.化合物的结构经元素分析,IR,1H NM R和M S确认,并对其波谱性质进行了讨论.

A series of 1,2,4-triazol [3,4-b]-1, 3,4-thiadiazines were synthesized ,their structure were characterized by elemental analysis, IR, ^1H NMR and MS spectra.