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非那雄胺临床应用进展 被引量:6

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摘要  目的:介绍非那雄胺临床应用拓展。方法:检索近年来有关非那雄胺药理作用、药动学和临床应用的文献。结果:非那雄胺是一种5α 还原酶的竞争性抑制剂,能降低血循环和毛囊等处的双氢睾酮的浓度。结论:非那雄胺除可用于治疗良性前列腺增生,还可用于男性型脱发以及预防前列腺癌。
作者 齐江洪
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2005年第2期159-160,共2页 Chinese Journal of Hospital Pharmacy
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参考文献9

  • 1崔京,黄健,方银杏.非那雄胺的药理和临床应用[J].国外医药(合成药.生化药.制剂分册),2002,23(1):35-37. 被引量:7
  • 2赵辨.保法止~(非那雄胺片)[J].临床皮肤科杂志,2002,31(5):307-307. 被引量:11
  • 3虞瑞尧.口服保法止治疗雄激素性脱发[J].中国新药杂志,1999,8(10):665-667. 被引量:3
  • 4Meconnel JD, Bruskewitz R, Walsh P, et al. The effect of finasteride on the risk of actue urinary retention and the need for surgicol treatmant among men with benign prostatic hyperplasia[J]. N Engl J Med, 1998,338:557.
  • 5Kaufman KD,Olsen EA,Whiting D,et al. Finasteride in the treatment of men with androgenetie alopecia[J]. J Am Aead Dermatol,1998,39:578.
  • 6杨淑霞,季素珍,陈伟,王丹,汪科,王卉,王爱平,韩钢文,刘玲玲,杨海珍,朱学骏.非那雄胺治疗男性雄激素源性秃发的随机、双盲、安慰剂对照临床研究[J].中国临床药理学杂志,2002,18(1):3-6. 被引量:12
  • 7ThomsonIM.非那雄胺对前列腺癌发生的影响[J].中国医学论坛报,2003,29(27):19-19.
  • 8The Finasteride Male pattern hair loss study Group. Long-term(5-year)multinational experience with finasteride lmg in the treatment of men with androgenetic alopecia[J]. Eur J Dermatol, 2002, 12(1):38.
  • 9孙华摘.[N].中国医学论坛报,2004,30(13):6.

二级参考文献15

  • 1[1]Montagna W, Camacho F Alopecias due to follicular miniaturization. Androgenetic alopecia. In: Camacho F, Montagna W, editor. Trichology. Spain: Grupo Aula Medica, 1997:313~316.
  • 2[2]Whiting DA. Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male pattern androgenetic alopecia. J Am Acad Dermatol,1993;28:755~763
  • 3[3]Drake L, Hordinsky M, Fiedler V, er al. the effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia. J Am Acad Dermatol,1999;41:550~554.
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  • 5[5]α-reductase deficiency in man: an inherited form of male pseudohermaphroditism. Science, 1974; 186:1213~1215.5.Eicheler W, Dreher M, Hoffmann R. er al. immunohistochemical evidence for differential distribution of 5a-reductase isoenzymes in human skin. Br J Dermatol,1995:133:371~376.
  • 6[6]Gormley GJ, Stoner E, Bruskewitz RC, Imperato-McGinley J, et al.The effect of finasteride in men with benign prostatic hyperplasia.N Engl J Med, 1992;327:1185~1191.
  • 7[7]McConnell JD, Wilson JD, George FW, et al. Finasteride, an inhibitor of 5α-reductase, suppresses prostatic dihydrotestosterone in men with benign prostatic hyperplasia. J Clin Endocrinol Metab. 1992;74:505~508.
  • 8[8]Dallob AL, Sadick NS, Unger W, et al. The effect of finasteride, a 5α-redectase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. J Clin Endocrinol Metab, 1994;79:703~706.
  • 9[9]Kaufman KD, Olsen EA, Whiting D, et al. Finasteride in the treatment of men with androgenetic alopecia. J Am Acad Dermatol, 1998;39:578~588.
  • 10[10]Leyden J, Dunlap F, Miller B, et al. Finasteride in the treatment of men with frontal male pattern hair loss. J Am Acad Dermatol,1999;40:930~937.

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引证文献6

二级引证文献50

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