胶原蛋白海绵在乳腺癌改良根治术中的应用效果观察

The application of collagen sponge in modified eradicative operation of breast cancer

目的探讨胶原蛋白海绵在乳腺癌改良根治术中应用的价值。方法将156例乳腺癌患者随机分成两组,对照组术后常规采取加压包扎持续负压引流,实验组则联合使用胶原蛋白海绵,分别观察两组置管时间、皮下积液和皮瓣坏死的发生率。结果实验组的置管时间(4.8±1.3)d明显短于对照组(6.3±2.7)d,有显著性差异(P<0.01),实验组皮下积液和皮瓣坏死的发生率分别为1.3%和2.6%,明显少于对照组的10.3%和11.5%,有显著性差异(P<0.05)。结论在乳腺癌改良根治术后引流管持续负压引流联合应用胶原蛋白海绵可缩短置管时间,减少皮下积液和皮瓣坏死的发生率。

Objective To discuss the value of collagen sponge used in the modified eradicative operation of breast cancer. Methods One hundred and fifty-six patients of breast cancer were randomly divided into two groups. The control group introduced pressure dressing and persistent negative pressure drainage, and the experimental group combined using of collagen sponge with negative pressure drainage. The remaining time of drainage tube, incidences of fluidity under skin and necrosis of skin flap were observed. Resuits The remaining time of drainage tube （4.8±1.3）d in the experimental group was outstanding shorter than the control group （6.3±2.7）d（P〈0.01）, incidences of fluidity under skin and necrosis of skin flap in the experimental group were significantly lesser （1.3% and 2.6% respectively）, compared with the control group （10.3% and 11.5% respectively） （P〈0.05）. Conclusion The use of collagen sponge combined with persistent negative pressure drainage can reduce the remaining time of drainage tube, the incidences of fluidity under skin and necrosis of skin flap.