电针治疗精神药物所致肥胖症疗效观察

Observation on therapeutic effect of electroacupuncture on obesity induced by antipsychotics

目的寻找治疗精神药物所致肥胖症的有效疗法。方法对101例正在服用抗精神病药物期间出现肥胖症患者,随机分为观察组(51例)与对照组(50例)。观察组每日电针治疗1次,穴取曲池、足三里、丰隆、上巨虚、下巨虚,4周为一疗程,连续治疗2个疗程;对照组不针刺。采用简明精神病量表(BPRS)评定疗效,副反应量表(TESS)评定不良反应。结果观察组临床有效率54.9%,优于对照组的10.0%(P<0.05),BPRS减分率分别为24.92%、28.62%,两组均无不良反应。结论电针治疗精神药物所致肥胖症疗效好,能提高患者对精神药物的依从性,无副作用。

Objective To find out an effective therapy for obesity induced by antipsychotic agents. Methods One hundred and one cases of obesity who were being treated with antipsychotic agents were randomly divided into an observation group and a control＇ group. The observation group were treated with electroacupuncture at Quchi （LI 11）, Zusanli （ST 36） , Fenglong （ST 40）, Shangjuxu （ST 37） and Xiajuxu （ST 39）, once a day for 8 weeks; and no treatment was given to the control group. The Brief Psychiatric Rating Scale （BPRS） was used for assessment of therapeutic effect and the Treatment Emergent Symptom Scale （TESS） for adverse effects. Results The clinically effective rate of the observation group （54.9 % ） was superior to the control group （10.0 % ） with a significant differ- ence between the two groups （P〈0.05）. The BPRS score-reducing rate was 24.92% and 28.62% in the both groups respectively, and with no adverse effects. Conclusion Electroacupuncture has a good therapeutic effect on obesity induced by antipsychotic agents, and it improves the patient＇s compliance with no adverse effect.