914例抗菌药物应用分析

Analysis of Antibacterial Agents Use in 914 Patients

目的了解我院住院患者抗菌素使用率及合理性。方法调查2004年10月全院各科出院病人1145例,对使用了抗菌素的病例分别按治疗性用药与预防性用药的合理性来进行评价。结果抗菌素的使用率为79.81%,按治疗性应用基本原则评价,合理应用者59.1%,基本合理者24.8%,不合理者16.1%;按预防性应用基本原则评价,合理应用者30.3%,基本合理者40.5%,不合理者29.2%。结论预防性用药是导致抗菌药物应用率高的主要原因,在抗菌素应用方面,要加强管理,严格掌握用药指征及其合理性。

Objective To calculate the proportion and evaluate the appropriateness of antibacterial drug use of the in- patients in our hospital. Method The 1, 145 discharges from all department- wards in October 2004 were reviewed to find out the cases that were received antibiotics in accordance with the appropriateness of therapeutic and of prophylactic drug use. Results The proportion of patients received antibiotics was ＂79.81%, among them, in according to the basic principle of therapeutic use, rational use accounted for 59. 1%, basically rational use was 24.8%, and irrational use was 16. 1%. As according to the basic principle of prophylactic use, the rational use was 30.3 %, the basically rational use was 40.5 %, and irrational use was 29.2 %. Conclusions Prophylactic drug use is the main reason for the high ratio of use of antibiotics. In the aspect of antibiotics use, the management is required to be strengthened by strictly keeping informed on the indications as well as appropriateness.