大鼠最后区内神经降压肽电镜免疫细胞化学定位

ELECTRON MICROSCOPIC IMMUNOCYTOCHEMICAL LOCALIZATION OF NEUROTENSIN IN THE AREA POSTREMA OF RAT

采用电镜免疫细胞化学技术观察了大鼠最后区内神经降压肽样免疫反应神经成分的超微结构。免疫反应产物可见于核周质、树突、轴突及其终末内。神经降压肽样免疫反应轴突终末与未标记树突形成轴-树突触。未标记轴突终末与神经降压肽样免疫反应树突亦可构成轴-树突触。此外,神经降压肽样免疫反应轴突终末可与血管和神经胶质胞体相邻或者直接接触。

Electron microscopic immunocytochemistry was empolyed to examine the ultrastructure of neurotensin-like immunoreactive (NT-LI) components in the area postrema of rat. NT-LI products were found in perikarya, dendrites. axons and terminals. It was only found that some NT-LI terminals svnapsed with unlabeled dendrites and unlabeled terminals with NT-LI dendrites. In addition, close approximations or direct contacts between NT-LI terminals and blood vessels or neuroglial cell bodies were observed.