菲立磁增强MRI对局灶性肝病的检出价值

The Detection Value of Focal Hepatic Lesions with Feridexs-Enhanced MR Imaging

目的 :着重探讨菲立磁增强扫描对局灶性肝病的检出价值。方法 :收集经螺旋CT增强扫描及菲立磁MRI增强扫描且临床、手术病理证实局灶性肝病 2 6例 5 7个病灶 ,采用分组盲法ROC曲线分析对比评价菲立磁增强MRI与螺旋CT增强扫描对局灶性肝病的检出价值。结果 :联合平扫MRI+增强MRI与其它三种方法之间比较 ,Az最大为 0 975 0 ,P <0 0 5 ,单独菲立磁增强MRI的Az=0 9315虽然大于平扫MRI的Az=0 92 2 6 ,但两者间差异无显著性 ,P >0 0 5 ,CT与其它三种方法之间比较 ,病灶检出Az =0 82 70最小 ,P <0 0 5。结论 :菲立磁增强MRI对肝局灶性病变的检出价值优于螺旋CT增强扫描。联合分析平扫 +菲立磁增强MRI的肝局灶性病灶的检出价值优于单独分析菲立磁增强法。

Abstract： Objective： We compared radiologist＇s pefformance on combined unenhanced and feridexs- enhanced MR imaging with their performance on helical CT enhanced, unenhanced MRI, and feridexs - enhanced MR alone imaging for the detection of local hepatic lesions. Methods： MR images and CT seans obtained in 26 patients with 57 local hepatic lesions were analyzed with ROC analysis. The imaging of patient were divided into 4 groups including combined unehanced and feridexs - enhanced MR imaging group, helical CT enhanced group, unenhanced MRI group, and Feridexs - enhanced MR alone group. Results： The combined approach resulted in larger area under the ROC curve （Az = 0.9750） and accuracy （86.8%） （ P 〈 0.05）, as compared with the others methods. Although the area under the ROC curve of Feridexs - enhanced MR alone group is larger than that of unenhanced group, there are no significant difference between this two groups in statistics （ P 〉 0.05）. The area under the ROC curve of CT group is the most smallest as compare with the other groups （Az=0.8270, P〈0.05）. Conclusion： Feridexs - enhanced MR imaging was more accurate than enhanced helical CT scan in detection of local hepatic lesion. The combined analysis of unenhanced and feridexs - enhanced images was more accurate in the detection of focal hepatic lesions than was review of feridexs - enhanced images alone.