穴位贴磁药对肝炎后肝硬化患者肝功能的保护

Protective actions of acupoint magnetic medicated plaster therapy on hepatic function in the patient of cirrhosis after hepatitis

目的:观察穴位贴磁药对肝炎后肝硬化的临床治疗效果。方法:将120例乙型肝炎后肝硬化患者随机分为2组,对照组60例采用常规护肝药治疗,治疗组60例常规保肝治疗基础上加用穴位贴磁药疗法治疗,连用2～6个疗程。观察临床症状、肝功能、乙肝病毒血清标志及肝纤维化指标。结果:治疗组痊愈显效率65.0%,总有效率95.0%;对照组痊愈显效率43.3%,总有效率91.7%。HBeAg转阴率治疗组为13.3%,对照组为8.3%;两组肝纤维化指标下降明显,差异均有显著性意义(P<0.05)。两组治疗后谷丙转氨酶、血清总胆红素均有下降趋势,但差异无显著性意义(P>0.05)。结论:穴位贴磁药能改善肝炎后肝硬化临床症状,迅速恢复肝功能,能使血清肝纤维化指标降低,是提高肝炎后肝硬化整体疗效且能长久施治的有效措施。

Objective To observe the therapeutic effect of acupoint magnetic medicated plaster therapy on cirrhosis after hepatitis. Methods One hundred and twenty patients with cirrhosis after hepatitis were randomly divided into 2 groups. The control group （n =60） were treated by the hepatic protective therapy （diammonium glyeyrrbiznate, Silymarin, compound Tansbin, vitamin E）, and the treatment group were treated by the liver-protective therapy and acupoint magnetic medicated plaster therapy, for 2 - 6 therapeutic courses. Clinical symptoms, hepatic function, serum markers of hepatitis B virus and indexes of hepatic fibrosis were investigated. Results The markedly effective rate and the total effective rate were 65.0% and 95.0% in the treatment group, and 43.3% and 91.7% in the control group , respectively. The returning negative rate was 13.3% in the treatment group and 8.3% in the control group, and the serum indexes of hepatic fibrosis decreased significantly, with significantly differences （all P 〈0. 05）. Conclusion Acupoint magnetic medicated plaster therapy can improve clinical symptoms, rapidly restore hepatic function, decrease serum indexes of hepatic fibrosis in the patient of cirrhosis after hepatitis.