头穴透刺对急性高血压性脑出血患者血浆ET、CGRP的影响

Effects of scalp penetration acupuncture on plasma endothelin (ET) and calcitonin gene related peptide (CGRP) contents in the patient of acute intracerebral hemorrhage

目的探讨头穴透刺治疗急性脑出血的作用机制。方法将60例急性脑出血患者随机分为头穴透刺组(30例)和西药对照组(30例)。两组基础疗法相同,头穴透刺组再加患侧百会透太阳针刺治疗,比较两组治疗前后血浆内皮素(ET)、降钙素基因相关肽(CGRP)水平的变化。结果头穴透刺组治疗14d后血浆ET水平明显低于西药对照组(P<0·01),血浆CGRP水平明显高于西药对照组(P<0·01)。结论头穴透刺对急性脑出血患者血浆ET、CGRP水平有明显良性调节作用。头穴透刺是通过调节脑出血患者ET、CGRP异常水平来达到治疗目的,从而改善患者的预后。

Objective To study the mechanism of scalp penetration acupuncture treating acute cerebral hemorrhage （ACH）. Methods The treatment group （n=30） and the control group （n：30） were treated with the same basic therapy, but scalp penetration acupuncture was added to the treatment group. Changes of plasma ET and CGRP contents were compared. Results After treatment for 14 days, the content of plasma ET in the treatment group was significantly lower than that in the control group （P〈0.01）. Moreover, the content of plasma CGRP was significantly higher than that in the control group （P〈0.01）. Conclusion Scalp penetration acupuncture is able to improve the prognosis of the patient with ACH by means of regulating the contents of plasma ET and CGRP.