隔药灸治疗原发性痛经临床观察

Clinical observation on medicine-separated moxibustion for treatment of primary dysmenorrhea and study on the mechanism

目的:观察隔药灸疗法治疗原发性痛经的临床疗效及对自身激素水平的影响。方法:将96例原发性痛经患者随机分为治疗组48例,采用隔药灸疗法;对照组48例,服月月舒冲剂。连续治疗3个月经周期后进行观察比较。结果:治疗组愈显率、有效率分别为87.5%,100.0%,明显优于对照组的29.2%、83.3%;组间比较差异有非常显著性和显著性意义(P<0.01,P<0.05)。治疗后经血的前列腺素含量和经期血浆催产素含量均显著降低(P<0.01)。结论:隔药灸疗法治疗原发性痛经疗效可靠,其作用机制可能通过调节患者异常的前列腺素及血浆催产素水平而发挥疗效。

Objective To observe clinical therapeutic effect of medicine-separated moxibustion on primary dysmenorrhea and study on the mechanism. Methods Ninety-six cases of primary dysmenorrhea were randomly divided into a treatment group and a control group, 48 cases in each group. They were treated respectively with medicine separated moxibustion and Yueyueshu Perfusing Powder for 3 consecutive months. Results The markedly effective and cured rate and the total effective rate were 87.5% and 100.0% in the treatment group, and 29.2% and 83.8% in the control group with significant differences between the two groups （P〈0.01 and P〈0.05）. After treatment, blood prosglanding F2 content in menorrhea blood and oxytocin level in plasma during menstruation decreased significantly as compared with those before treatment （P〈0. 01）, Conclusion The medicine-separated moxibustion has a reliable therapeutic effect on primary dysmenorrhea and the therapeutic effect is exerted possibly by regulating abnormal prosglanding and oxytocin levels in the patient.