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白色念珠菌耐药蛋白(Cdr1p)表达及调控机制研究进展 被引量：2

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摘要 白色念珠菌多药耐药机制主要与含能量依赖型ATP结合盒的转运蛋白(ATP-b ind ing cassette transporters,ABCT)的过度表达有关。白色念珠菌有10种ABCT,只有Cdr1p和Cdr2p与多药耐药相关,其编码基因cdr1和cdr2的mRNA水平增高与基因扩增和转录后调控无关,主要是基因转录增加的结果。主要针对Cdr1p的分子结构、功能和表达及调控机制的研究进展进行了综述。
作者 郭慧君 夏忠弟
机构地区 中南大学湘雅医学院微生物学教研室
出处 《国外医药（抗生素分册）》 CAS 2005年第6期244-247,共4页 World Notes on Antibiotics
关键词 白色念珠菌 多药耐药 Cdr1P 转录调控
分类号 R379 [医药卫生—病原生物学]
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参考文献26

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同被引文献24

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国外医药（抗生素分册）
2005年 第6期

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