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轻度认知功能障碍与早期阿尔茨海默病诊断的外周标志 被引量：1

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摘要 轻度认知功能障碍作为阿尔茨海默病的前期阶段,有着与阿尔茨海默病不同程度相似的外周标志。这些外周标志的研究进展主要表现在神经心理认知改变、生物学标志 Aβ和 Tau 蛋白以及分子生物学标志 ApoE 等方面;重视轻度认知功能障碍,认识早期阿尔茨海默病外周标志对阿尔茨海默病的早期诊断和早期干预有重要的意义。
作者 司俊霞 谈跃
机构地区 昆明医学院第二附属医院老年病科
出处 《国外医学（老年医学分册）》 2005年第6期241-243,共3页 Foreign Medical Sciences(Geriatrics)
基金 云南省教委资助课题(05-206)
关键词 轻度认知 阿尔茨海默病 诊断 轻度认知功能障碍 早期干预 早期诊断 外周 分子生物学标志 TAU蛋白 不同程度
分类号 R749.161 [医药卫生—神经病学与精神病学]
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参考文献9

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同被引文献20

  • 1张连春,陶华英.轻度认知功能障碍转化为阿尔茨海默病的预测研究[J].医学综述,2007,13(20):1575-1577. 被引量：3
  • 2Petersen RC. Mild cognitive impairment: transition between aging and Alzheimer's disease[J]. Neurologia,2000,15:93-101.
  • 3Tarkowski E, Andreasen N, Tarkowski A, et al. Intrathecalinflammation precedes development of Alzheimer's disease[J]. J Neurol Neurosurg Psychiatry,2003,74:1200-1205.
  • 4Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease[J]. Lancet Neurol,2003,2:605-613.
  • 5Silbert LC, Quinn JF, Moore MM, et al. Changes in premorbid brain volume predict Alzheimer's disease pathology[J]. Neurology, 2003,61:487-492.
  • 6Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: clinical chal=acterization and outcome[J]. Arch Neurol,1999,56:303-308.
  • 7American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders[M]. third edn, revised. Arlington, VA, USA: American Psychiatric Association,1987:|.
  • 8Mckhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer' s Disease[J]. Neurology,1984,34:939-944.
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  • 10Herukka SK, Hallikainen M, Soininen H, et al. CSF A~i42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment [J]. Neurology,2005,64:1294 - 1297.

引证文献1

二级引证文献4

国外医学（老年医学分册）
2005年 第6期

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