冬虫夏草对运动小鼠肝组织自由基代谢及血清酶活性的影响

Effect of Cordyceps Sinensis on Free Radical Metabolism and Serum Enzyme in Rats Liver

通过建立灌服冬虫夏草小鼠的力竭游泳训练实验模型,测定了小鼠肝组织的超氧化物歧化酶(SOD)的活性、丙二醛(MDA)的水平以及血清谷丙转氨酶(GPT)的活性。实验结果显示,灌服冬虫夏草后,小鼠游泳运动能力明显提高;肝组织SOD活性显著高于各自对照组;MDA含量显著低于各自对照组。说明冬虫夏草具有较强的抗自由基损伤和抗脂质过氧化损伤的作用,服用冬虫夏草可减轻运动所产生的内源性自由基对小鼠的伤害。另外,冬虫夏草对小鼠肝细胞膜有保护作用,可减少组织酶的外泄。

By setting up the exhaustive swimming rats model, the activity of Liver SOD, the quantity of MDA and the serum GOT are all valued. The results indicat that after the rats took cordyceps sinensis, their physical ability improved remarkably; the activity of Liver SOD appeared superior to the control group; the quantity of MDA turned lower than the control group, which shows that cordyceps sinensis enjoys much stronger influence on the anti - oxidation and anti - free - radical. Besides, their ability of counteracting the free radical of Liver jumped to a high level. Furthermore, cordyceps sinensis can also been used to protect the integrality of Liver cell membrane; to reduce the escape of enzyme from the cell.