奥亭止咳露治疗COPD急性期的疗效观察

Efficacy Observation of COFETOL Cough Syrup in Treating Acute Exacerbation COPD Patients

目的观察常规疗法加奥亭止咳露治疗COPD急性期的疗效和安全性。方法100例COPD急性期的病人随机分为2组。治疗组50例,在常规治疗基础上加用奥亭止咳露10ml,po,tid,选用7d。另有常规治疗组50例,仅用吸氧、抗感染、必嗽平、改善通气等常规处理。结果治疗组总有效率96%与对照组64%比较,差别有显著意义(P<0.05)。2组均未发现严重不良反应。结论奥亭止咳露可有效改善COPD急性期患者的症状,是该病有效的辅助治疗药物之一。

Objective To explore the efficacy and safety of COFETOL cough syrup in treating acute exacerbation COPD （AECOPD）. Methods hundred patients of AECOPD were randomized to divide into two groups. Fifty patients of AECOPD treatend with COFETOL cough syrup 10ml, po, qd for 7d, in addition to conventional therapy （inhalation of oxygen and anti-infection therapy etc）. Other 50 patients served as control were treated with conventional therapy only. Results The total response rate was 96% and 64% for treatment group and comparison group respectively （P〈0.05）. No serious adverse reactions were found in 2 groups. Conclusions COFETOL cough syrup was one of the effective assistant agents in treating AECOPD, because of the role it plays in the improvement of symptoms.