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高压氧治疗对缺血性脑卒中患者血浆中PC、PS及AT-Ⅲ的影响 被引量:12

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摘要 目的:观察高压氧(HBO)治疗缺血性脑卒中对蛋白C(PC)、蛋白S(PS)和抗凝血酶Ⅲ(AT-Ⅲ)的影响。方法:用血凝仪及配套试剂盒检测采用完全随机分组的137例HBO治疗组患者、97例常规治疗组患者及40例正常对照组血浆PC、PS和AT-Ⅲ水平。结果:常规治疗组PC、PS和AT-Ⅲ水平开始时比正常对照组低,差异显著,P<0.01;第10天仍低于对照组,差异显著,P<0.05;第20天恢复正常,无显著性差异,P<0.05。高压氧治疗组PC、PS和AT-Ⅲ水平开始时比正常对照组也低,P<0.01;第10天、第20天与对照组相比无显著性差异,P>0.05。结论:HBO能调节PC、PS和AT-Ⅲ水平,可减轻因缺血、血管损伤引起的凝血、抗凝及纤溶系统异常,对缺血性脑卒中减轻脑损伤的治疗,预防复发有显著效果。
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2005年第11期833-834,共2页 Journal of Nanjing Medical University(Natural Sciences)
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