晚发性维生素K缺乏症36例临床分析与预防

Clinical analysis and prevention of 36 cases of delayed vitamin K deficiancy

目的:探讨婴儿晚发性维生素K缺乏症的临床特点,提高对本病的认识,加强预防。方法:回顾性分析近4年我院儿科收治的36例婴儿晚发性维生素K缺乏症的临床资料。结果:治愈28例,治愈率77.78%;死亡5例,死亡率13.89%;放弃治疗3例,8.33%。结论:单纯母乳喂养婴儿本病发生率高,对所有新生儿从出生至生后3个月定期小剂量补充维生素K1可预防本病发生。对本病的早期诊断,早期有效治疗对提高治愈率、减少病死率有重要临床意义。

Objective：To explore the clinical feature and prevention of delayed vitamin K deficiency in infants. Methods：The clinical data of 36 infants with delayed vitamin K deficiency who had been admitted to paediatric ward in our hospital during the last 4 years were analyzed retrospectively. Results ：28 cases were cured with a cure rate of 77.78% ; 5 cases died with a mortality rate of13.89% ; 3 cases gave up treatment which accounts for 8.33%. Conclusion ：The incidence rate of delayed vitamin K deficiency is high in infants on pure breastfeeding,and it could be prevented by periodical administration of supplementary vitamin KI in small doses to all infants from birth to 3 months. The early diagnosis and proper treatment of delayed vitamin K deficiency are of much clinical significance in increasing cure rate and reducing mortality rate.