肝脏炎性肌纤维母细胞瘤

Inflammatory myofibroblastic tumor of liver

目的探讨肝脏炎性肌纤维母细胞瘤的临床病理特征、诊治和预后。方法总结了一例肝脏炎性肌纤维母细胞瘤病人的临床资料,并复习了国内外的文献,分析和归纳其临床表现、诊断和治疗。结果肝脏炎性肌纤维母细胞瘤的临床病理特征和预后如下:①常见于儿童和青少年;②临床症状常表现为贫血、发热、上腹部隐胀痛、体重下降等;③物理检查可见肝脏包块;④病理特征:该瘤由分化的肌纤维母细胞性梭形细胞组成,常伴大量浆细胞和(或)淋巴细胞浸润;⑤外科切除或肝移植后,预后佳,无复发。结论肝脏炎性肌纤维母细胞瘤有其特征性的临床表现,经手术切除后可治愈。

Objective To assess the diagnosis and treatment for inflammatory myofibroblastic tumor of liver. Methods The demographic and clinical data of a case was summarized and analyzed. Literature review was also made meanwhile. Results The clinicopathological profile and prognosis are as follows： ① it usually occurs in juvenile; ②clinical manifestations are anemia,fever,upper abdominal pain and body weight loss; ③tumor mass can be determined by US, CT or MRI in liver; ④ pathological examination shows prominent spindle myofibroblasts and infiltration of plasma ceils or lymphocytes;⑤ mass resection or liver transplantation can lead to satisfactory prognosis. Conclusions Inflammatory myofibroblastic tumor of liver shows specific clinicopathological features, and it can be cured by surgery.