绍兴地区甲状腺结节性疾病的尿碘检测与分析

Measurement and analysis of urinary iodine concentrations of thyroid nodal diseases persons in Shaoxing

目的探讨绍兴地区补碘后甲状腺结节性疾病与尿碘的关系。方法测定甲状腺结节性疾病患者101例尿碘含量,并以甲状腺正常的其他疾病患者76例作为正常对照;同时检测甲状腺结节性疾病患者血FT4、TSH、TPOAb、TGAb含量。结果在甲状腺结节性疾病患者中尿碘大于300μg/L占85.15%,对照组只占11.81%,P<0.001,差异有显著性。甲状腺结节性疾病组尿碘大于2000μg/L以上者占57.43%,而对照组尿碘均小于2000μg/L。本组病例女性多于男性,30岁以上者发病率远高于30岁以下者。结论绍兴地区补碘后甲状腺结节性疾病与高尿碘有关,补碘后碘缺乏已不是结节性甲状腺疾病患者的主要发病原因。对于高尿碘的人群补碘值得深入探讨,尿碘的测定有助于指导个体化补碘。

Objective To investigate the relationship between thyroid nodal diseases and unirary iodine after salt iodization in Shaoxing.Methods measurement of iodine concentrations of 101 cases of thyrioid nodal diseases and 76 cases of non-thyroid diseases, and their sera were measutred for FT4,TSH, TPOAb, TGAb. Results Iodine concentrations of thyroid nodal diseases cases over 300μg/L was 85.15%,but only 11.81% in non-thyroid diseases cases,statistic difference was sigrificant; Iodine concentrations of thyroid nodal diseases cases over 200μg/L was 5743%, but there were not over 200μg/L in non-thyroid diseases cases. Woment was more common in thyroid nodal diseases cases, and the high incidence of thyroid nodal diseases in over 30-years persons. Conchuston Thyroid nodal diseases are related to urinary iodinge after salt iodizstion in Shaoxing, and iodine deficiency is not the msin reason of thyroid nodal diseases after salt iodization in Shaoxing. Further investigation were needed to take iodinization salt in thyroid nodal diseases persons, and measurement of iodine concentrations is necessary for take inodinizstion salt in individualization.