摘要
目的:探讨尿毒症患者肾移植后睾丸生精功能的改变。方法:比较30例男性尿毒症患者,肾移植前后精液参数变化及精子超微结构改变。结果:肾移植术后3个月精子活力与移植前比较显著升高[(70.08±2.86)%vs(36.04±8.01)%,P<0.01],活率显著增加[(76.15±3.75)%vs(39.27±4.14)%,P<0.01],运动速度显著加快[(16.80±1.11)μm/svs(8.43±2.01)μm/s,P<0.01]。精子超微结构发现,肾移植后支持细胞、顶体及线粒体的结构趋向正常。结论:肾移植可显著改善尿毒症患者的生精功能。
： Objective： To study the changes of testicular spermatogenic function after kidney transplantation. Methods： Thirty male patients with uremia underwent kidney transplantation. Semen analyses were made and sperm uhrastructural changes were studied before and after the operatioin. Results： Sperm viability, motility and movement velocity were significantly higher in the postoperative group than in the preoperative group [ （ 70. 08 ± 2. 86 vs （36.04±8.01） ], [（76.15±3.75）% vs （39.27±4.14）%], [（16.80±1.11 ） μm/s vs （8.43 ±2.01 ） ] μm/s, respectively（P 〈 0.01 ）. Sertoli cell, acrosome and mitochondria structures inclined to norreal after kidney transplantation. Conclusion ： Kidney transplantation can significantly improve spermatogenic function in patients with uremia. Natl J Androl,2005 ,11 （ 11 ） ：822-824
出处
《中华男科学杂志》
CAS
CSCD
2005年第11期822-824,共3页
National Journal of Andrology
关键词
尿毒症
肾移植
生精功能
uremia
kidney transplantation
spermatogenic function
