万艾可治疗老年糖尿病性勃起功能障碍疗效分析

Effects of Sildenafil on Erectile Dysfunction in the Aged Men with Diabetes

目的:观察万艾可治疗我国老年糖尿病性勃起功能障碍患者的临床安全性和疗效。方法:用国际勃起功能问卷的勃起功能评分、性生活日记的问题2及问题3和总体评价问卷评估452例患者服用万艾可前后勃起功能状况。结果:服药后,患者的国际勃起功能问卷的勃起功能评分提高程度、性生活日记问题2和问题3作肯定回答的患者百分率,以及总体评价问卷回答百分率均显著高于基线值,统计学分析差异有极显著性(P<0.01)。结论:万艾可显著改善糖尿病性勃起功能障碍患者的勃起能力,提高性生活质量。

Objective： To evaluate the efficacy and safety of sildenafil on erectile dysfunction in the aged men with diabetes. Methods ： One hundred and ten patients aged 55 years old above with type Ⅰ or Ⅱ diabetes and a minimum 3-month history of ED were studied. Patients were instructed to take one dose of their treatment orally at any time before anticipated sexual activity. Changs from baseline in mean scores on the erectile function domain of the International index of Erectile Function and changes from baseline in the proportion of＂ yes＂ responses to question 2, and 3, of the Sexual Encounter Profile were coprimary outcome measures. Results ： Treatment with sildenafil significantly improved all primary efficacy variables. Conclusion： Sildenafil therapy significantly enhanced erectile function and was well tolerated by men with diabetes and ED. Natl J Androl,2005,11（11） ：841-842,846