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雌激素与雄性生殖 被引量：6

Role of Estrogen in Male Reproduction
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摘要 雌激素与男(雄)性生殖密切相关。人和哺乳动物体内芳香化酶(Ar)参与合成雌激素,雌激素与特异受体(ERα、ERβ)结合,行使其生物学效应。雌激素受体和Ar在雄性生殖器官所有发育阶段几乎都有表达,并通过对生殖细胞、Sertoli细胞、Leyd ig细胞和附睾的多方面调节而发挥作用。 Estrogen plays an essential role in male reproduction. In human and other mammalians, a number of tissues express aromatase and hence synthesize estrogen. ERs and aromatase are present at all developmental stages of tile male reproductive organs in many mammalian species. Estrogen is important in different aspects in male reproductive physiology, including its effects on germ cells, Sertoli cells, Leydig cells and epididymal functions. Natl J Androl,2005,11 （11）：847-850
作者 潘艺青 徐晨
机构地区 上海第二医科大学组织学与胚胎学教研室上海市生殖医学重点实验室
出处 《中华男科学杂志》 CAS CSCD 2005年第11期847-850,共4页 National Journal of Andrology
关键词 雌激素 雄性生殖 estrogen male reproduction
分类号 R33 [医药卫生—人体生理学]
  • 相关文献

参考文献28

  • 1Jensen TK, Toppari J, Keiding N, et al. Do environmental estrogens contribute to the decline in male reproductive health[J]? Clin Chem, 1995, 41(12 Pt 2):1896-1901.
  • 2Hess RA, Bunick D, Lee KH, et al. A role for oestrogens in the male reproductive system[J]. Nature, 1997, 390(4):509-512.
  • 3Tremblay GB, Tremblay A, Copeland NG, et al. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor[J]. Mol Endocrinol, 1997, 11(3):353-365.
  • 4Toda K, Okada T, Takeda K, et al. Oestrogen at the neonatal stage is critical for the reproductive ability of male mice as revealed by supplementation with 17-oestradiol to aromatase gene (Cyp19) knockout mice[J]. J Endocrinol, 2001, 168(3):455-463.
  • 5Kushner PJ, Agard DA,Greene GL, et al. Estrogen receptor pathways to AP-1[J]. J Steroid Biochem Mol Biol, 2000, 74(5):311-317.
  • 6童明汉,郭强苏,王如瑶,张君慧,高惠宝,吴明章.雌激素对大鼠附睾上皮细胞非基因组作用及其机制研究[J].解剖学杂志,2000,23(3):229-232. 被引量：2
  • 7van Pelt MM, de Rooij DG, van der Burg B, et al. Ontogeny of estrogen receptor-beta expression in rat testis[J]. Endocrinology, 1999, 140(1):478-483.
  • 8Saunders PT, Fisher JS, Sharpe RM, et al. Expression of estrogen receptor(ER ) occurs in multiple cell types, including some germ cells, in the rat testis[J]. J Endocrinol, 1998, 156(3):R13-R17.
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二级参考文献5

  • 1[1]Sharpe RM. Do males rely on female hormones?Nature, 1997,309: 447.
  • 2[2]Hess RA, Bunick D. A role for oestrogens in the male reproductive system. Nature, 1997, 390:509.
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  • 4[4]Revelli A, Massobrio M. Nongenomic action of steroid hormones in reproductive tissues. Endoc Rev, 1998, 19: 3.
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共引文献1

同被引文献31

  • 1Vincenzo Rochira,Antonio R. M. Granata,Bruno Madeo,Lucia Zirilli,Giuseppina Rossi,Cesare Carani.Estrogens in males: what have we learned in the last 10 years?[J].Asian Journal of Andrology,2005,7(1):3-20. 被引量：15
  • 2李和程,陈琦,王子明,甘为民,程伟,石涛,邱曙东,葛玲,王新阳.青春期前己烯雌酚暴露对大鼠性成熟后生精细胞凋亡的影响及其机制初探[J].中华男科学杂志,2006,12(9):814-817. 被引量：7
  • 3胡淼,杜鹃,陈莉.双酚A对小鼠睾丸细胞DNA损伤的研究[J].北华大学学报（自然科学版）,2007,8(4):311-313. 被引量：3
  • 4Wald M, Ross LS, Prins GS, et al. Analysis of outcomes of cryopreserved surgically retrieved sperm for IVF / ICSI [J]. J Androl, 2006, 27( 1 ):60-65.
  • 5WHO laboratory manual for the examination of human semen and spercervical mucux interaction [M]. 3rd. New York: Cambridge University Press, 1992: 1.
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  • 7Stanic P, Tandara M, Sonicki Z, et al. Comparison of protective media and freezing techniques for cryopresen, ation of human semen[J]. Eur J Obstet Gynecol Reprod Biol,2000,91 (1):65-70.
  • 8Carreau S, Delalande C, Silandre D, et al. Aromatase and estrogen receptors in male reproduction [J]. Mol Cell Endocrinol, 2006,246( 1/2 ) :65-68.
  • 9Brinster RL.Zimmermarm JW.Spermatogenesis following male germcell transplantution[J].Proc Nall Aeal Sol.USA.1994.91(24).11298-11302.
  • 10Johnson J.Baglcy J.Skaznik-Wikiel M,et al .Queyte generation in adult mammalian wvaries by putative germ cells in hone marrow and peripheral blond[J].Cell .2005.122(2).303-315.

引证文献6

二级引证文献45

中华男科学杂志
2005年 第11期

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