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药物洗脱支架联用普通金属支架治疗多支冠状动脉病变的疗效评价 被引量:1

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摘要 为探讨多支冠状动脉病变药物洗脱支架(DES)与普通金属支架(普通支架)联用预防再狭窄的疗效及安全性,对我院2002年6月-2004年12月连续801例行多支冠脉内支架置入术达到完全血运重建的冠心病患者分为3组:DES组206例,DES与普通支架联用组(联用组)158例,及普通支架组437例。比较3组支架术后近期及远期结果。3组冠心病危险因素、心功能、冠状动脉病变程度、支架术成功率及并发症发生率均无显著差异。联用组普通支架置入于31.3%的前降支病变(均为A-B1型病变)及81.6%的左回旋支病变和 69.9%的右冠状动脉病变。术后平均随访(17.3±13.9)个月,3组总随访率无显著差异。结果表明,与普通支架组相比,DES组和联用组造影再狭窄率明显降低,分别为21%比7.4%和9.0%(P均<0.05),且主要不良心脏事件发生率均较低,分别为18.4%比6.5%和9.9%(P均<0.05)。但DES组与联用组相比上述各指标无显著差异。结论:多支冠状动脉病变患者单用DES或合理联用普通支架后再狭窄降低,安全性近似,均优于单用普通支架。
出处 《沈阳部队医药》 2005年第6期364-368,共5页
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  • 1M. Hoffmann,G.S. Werner,M. Ferrari,B.M. Richartz,H.R. Figulla. Direkte koronare Stentimplantation ohne Vordilatation – eine neue therapeutische Strategie mit einem speziellen Ballonkatheter[J] 1999,Zeitschrift für Kardiologie(2):123~132

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  • 1胡大一.美国心脏病学学会第54届年会热点荟萃[J].中华心血管病杂志,2005,33(6):582-584. 被引量:12
  • 2Nath R, Amols H, Coffey C, et al. Intravascular brachytherapy physics:report of the AAPM Radiation Therapy Committee Task Group no. 60. American Association of Physicists in Medicine[ J]. Med Phys,1999,26(2) :119-152.
  • 3Naghavi M, Libby P, Falk E ,et al. From vulnerable plaque to vulnerable patient. A call for new definition and risk assessment strategies: part Ⅰ and part Ⅱ [ J ]. Circulation, 2003, 108 ( 15 ) : 1664-1778.
  • 4Falk E. Why do plaques rupture? [ J ]. Circulation, 1992,86 ( 6 Suppl) : Ⅲ30-Ⅲ42.
  • 5Bueke AP, Farb A, Malcom GT, et al. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly [J]. N Engl J Med,1997,336(18) :1276-1282.
  • 6Regar E, Serruys PW, Bode C, et al. Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent(RAVEL) :sirolimus-eluting stents inhibit restenosis irrespective of the vessel size [ J ]. Circulation, 2002,106( 15 ) : 1949-1956.
  • 7Moses JW, Leon MB, Popma JJ, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery[J]. N Engl J Med,2003,349(14) :1315-1323.
  • 8Schofer J, Schluter M, Gershlick AH, et al. Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary artery : double-blind, randomized controlled trial ( E-SIRIUS) [J]. Lancet,2003,362(4) :1093-1099.
  • 9Schampaert E, Cohen EA, Schluter M ,et al. The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions in small native coronary arteries (C-SIRIUS) [ J ]. J Am Coll Cardiol,2004,43(6) :1110-1115.
  • 10Bhatia V, Bhatia R, Dhindsa M. Drug-eluting stent: new era and new concerns[ J]. Postgrad Med J ,2004,80( 1 ) : 13-18.

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