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^(18)F-氟代脱氧葡萄糖PET和PET-CT在转移性骨肿瘤中的应用研究

Application study of ^(18)F-FDG PET and PET-CT on malignant bone metastases
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摘要 18F-氟代脱氧葡萄糖(18F-FDG)PET和PET-CT可直接显示转移到骨骼中的肿瘤组织,早期诊断转移性骨肿瘤,是较为敏感的一种方法。其与传统骨显像在临床应用中具有互补作用,不能相互替代,应针对不同情况具体对待。 ^18F-fluorodeoxyglucose （ ^18F-FDG ） PET or PET-CT can directly detect increased glucose metabolism of neoplastic cells nested in the skeleton, making it a sensitive method for assessment of bone metastases.
作者 刘建军 黄钢
机构地区 上海第二医科大学附属仁济医院PET-CT中心
出处 《国外医学（放射医学核医学分册）》 2005年第5期213-216,共4页 Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
基金 上海市教委重点发展基金(04BA03) 上海市百人计划第三轮重点资助(97BR012)
关键词 转移性骨肿瘤 18F-氟代脱氧葡萄糖 正电子发射体层显像 计算机体层成像 99Tcm-亚甲基二膦酸盐 bone metastases ^18F-fluorodeoxyglucose positron emission tomography computed tomography ^99Tc^m-methylene diphosphonate
分类号 R738.1 [医药卫生—肿瘤]
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参考文献11

  • 1Schirrmeister H, Guhlmann A, Eisner K, et al. Sensitivity in detecting osseous lesions depends on anatomic localization: Planar bone scintigraphy versus 18F PET [J]. J Nucl Med, 1999, 40 ( 10): 1623-1629.
  • 2Hawkins RA, Choi Y, Huang SC, et al. Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET[J]. J Nucl Med, 1992,33(5): 633-642.
  • 3Brenner W, Vernon C, Muzi M, et al. Comparison of different quantitative approaches to 18F-fluoride PET scans[J]. J Nucl Med, 2004, 45(9): 1493-1500.
  • 4Even-Sapir E, Metser U, Flusser G, et al. Assessment of malignant skeletal disease: initial experience with 18F-fluoride PET/CT and comparison between 18F-fluoride PET and 18F-fluoride PET/CT[J]. J Nucl Med, 2004, 45(2): 272-278.
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  • 8Uematsu T, Yuen S, Yukisawa S, et al. Comparison of FDG PET and SPECT for detection of bone metastases in breast cancer[J]. Am J Roentgenol, 2005, 184(4): 1266-1273.
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国外医学（放射医学核医学分册）
2005年 第5期

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