摘要
18F-氟代脱氧葡萄糖(18F-FDG)是目前最常用的肿瘤诊断药物,但由于其正常的生理分布,影响了一些肿瘤的诊断。本文主要介绍了11C标记的正电子药物:11C-甲硫氨酸、11C-胆碱、11C-乙酸盐在原发脑肿瘤、头颈部肿瘤、肺癌、肝癌、妇科肿瘤、前列腺癌、膀胱癌、骨及软组织肿瘤上诊断及分期、疗效监测的价值。研究表明,11C标记的肿瘤正电子药物是18F-FDG的一个重要补充。
^18F-fluorodeoxyglucose（ISF-FDG） was most wildly used radiopharmaxeuticals for tumors. It wasn＇t suitable for some malignant tumors because of it＇s normal biodistribution. We review some ^11C labeled radiopharmaceuticals, including ^11C-methionine, ^11C-choline and ^11C-acetate, for primary diagnosis and staging with brain tumors, head and neck cancer, lung cancer, liver tumors, gynecologic tumors, prostate cancer, bladder cancer, bone and soft tissue tumors, and the monitor value for radiotherapy. The ^11C labeled radiopharmaceuticals were very important complement of ISF-FDG.
出处
《国外医学（放射医学核医学分册）》
2005年第5期232-237,共6页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
