代谢信号对能量影响猪卵泡发育的作用

The Effects of Metabolic Signals on Swine Ovarian Follicular Development Influenced by Energy

动物体内的许多激素和因子通过内分泌活动把能量摄入和繁殖系统联系起来。卵巢上卵泡的发育是雌性动物繁殖系统中的重要因素,是繁殖性能的基础。猪的生产是人们生活中主要的肉类来源之一,能量对猪卵泡发育的影响日益受到关注。日粮能量水平的变化会影响到体内循环与营养代谢相关的激素和因子,而这些激素和因子的变化可能会作为代谢信号对卵泡的发育产生影响。这些代谢信号包括胰岛素、瘦素和胰岛素样生长因子-Ⅰ等。研究表明,代谢信号对下丘脑、垂体和卵巢均有影响。在胰岛素、瘦素和胰岛素样生长因子-Ⅰ等代谢信号的介导下,日粮能量营养因素通过改变下丘脑-垂体-卵巢轴的活性,对雌性动物的卵泡发育产生影响。

There are some kinds of hormones and factors, linking energy intake and reproductive system in a manner of incretion. The development of ovarian follicle plays a primary basic role in the reproductive function of female livestock. Porcine industry is the main source providing pork consumed in our daily life. Recent researches increasingly focus on the effects of energy intake on follicle development. The changes of dietary energy level may influence some circulating metabolism hormones and factors, which may impact the development of follicle, as metabolism signals including insulin, leptin and IGF-Ⅰ. It is demonstrated that these metabolism signals can act on the level of hypothalamic, pituitary and gonad. Mediated by these metabolism signals such as insulin, leptin and IGF-Ⅰ, dietary energy makes an impact on reproductive function of female livestock, by influencing the activity of hypothalamic-pituitary-gonad axis.