摘要
一氧化氮(NO)化学结构简单,性质活跃,广泛参与机体的生理、病理调节。在妊娠期,NO可降低血管对加压物质的反应性,降低外周阻力及血压。目前认为,NO产生减少是妊娠高血压征合征发病的重要原因,是导致母体妊娠期心血管系统发生血容量增加、血压下降、血液重新分布等生理性改变的重要因素,胎盘局部NO及其相关因子对胎盘功能和胎儿的生长发育有直接的影响作用。
Nitric oxide (NO), with simple chemistry structure, has participated in organism physiology and pathology regulation extensively. NO can reduce the reactivity of the pressurizing substances to blood vessel, reduce the peripheral resistance and blood pressure during the gestation. It is common thought that low-output of NO is the main cause of pregnancy-induced hypertension syndrome. And it is a major factor to lead to the maternal changes during gestation, such as, the increasing of blood capacity, the decreasing of blood pressure and the blood redistribution in the cardiovascular system. Some NO of placenta and related factors have direct effects on placental function and the development of foetus.
出处
《动物医学进展》
CSCD
2005年第11期36-38,共3页
Progress In Veterinary Medicine
关键词
一氧化氮
胎儿
胎盘
Nitric oxide (NO)
fetus
placenta